Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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826 – 840 of 4,235 results

826

Medchemexpress LLC Mebendazole-amine 5mg | 52329-60-9 | 237.26 g/mol | C14H11N3O | 5 MG

Mebendazole-amine is a research metabolite of mebendazole supplied as a high-purity solid for analytical and metabolic studies. Store protected from light and follow solvent storage recommendations for long-term stability.

Research metabolite of mebendazole.
High purity: 98.35%.
Molecular weight 237.26 g/mol; formula C14H11N3O.
Supplied in small vials suitable for analytical work (e.g., 5 mg).
Appearance: solid, white to off-white.
Storage: 4°C, protect from light; in solvent, -80°C up to 6 months or -20°C up to 1 month.

Pricing & Availability

827

eMolecules 873-42-7 | 3,5-dichloropyrazin-2-amine | Combi-Blocks | MFCD11040179 | 163.990 | C4H3Cl2N3 | 98.000 | Nc1ncc(Cl)nc1Cl | 5g | 232333226

3,5-dichloropyrazin-2-amine | Combi-Blocks | 873-42-7 | MFCD11040179 | 163.990 | C4H3Cl2N3 | 98.000 | Nc1ncc(Cl)nc1Cl | 5g | 232333226

Pricing & Availability

828

Medchemexpress LLC Olmutinib | 1353550-13-6 | 99.5% / 99.9% | 486.59 | 200 MG

Olmutinib is an orally active and irreversible third-generation EGFR tyrosine kinase inhibitor. It binds to a cysteine residue near the kinase domain and is used for Non-Small Cell Lung Cancer (NSCLC). This product is for research use only.

Orally active
Irreversible third-generation EGFR tyrosine kinase inhibitor
Binds to a cysteine residue near the kinase domain
Used for Non-Small Cell Lung Cancer (NSCLC)
For research use only

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829

AdipoGen Dihydroethidium

Chemical. CAS 104821-25-2. Formula C21H21N3. MW 315.41. Synthetic. Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.

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830

AdipoGen Dihydroethidium

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831

eMolecules 2246-44-8 | 2-Methylnaphthalen-1-amine | Ambeed | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 5g | 528570193

2-Methylnaphthalen-1-amine | Ambeed | 2246-44-8 | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 5g | 528570193

Pricing & Availability

832

Chem-Impex International, Inc. N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline | 16357-59-8 | MFCD00006703 | 25G

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, 16357-59-8, MFCD00006703, 25G

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833

Apexbio Technology LLC Belinostat (PXD101) 414864-00-9 200mg

Belinostat (PXD101) is a hydroxamic acid-based inhibitor targeting histone deacetylase (HDAC) enzymes Its mechanism involves the suppression of HDAC enzymatic activity leading to increased acetylation of histone proteins H3 and H4 within cells In biochemical assays using Hela cell extracts belinostat exhibits inhibitory activity against HDAC with an IC50 value of approximately 27 nM In tumor cell culture models belinostat induces cytotoxicity and represses cellular proliferation with reported IC50 values ranging roughly from 0 5 M to 10 M varying by cell type and origin making it suitable for research on epigenetic modulation in oncology specifically in studies of bladder prostate and related cancer cell lines

Pricing & Availability

834

Medchemexpress LLC Pravastatin sodium | 81131-70-6 | 99.4% | 200 MG

Pravastatin sodium is an HMG-CoA reductase inhibitor that acts against sterol synthesis, with an IC50 of 5.6 μM. It belongs to the statin drug class and is utilized alongside diet, exercise, and weight-loss strategies to lower cholesterol and help prevent cardiovascular disease.

Functions as an HMG-CoA reductase inhibitor.
Targets sterol synthesis.
Exhibits an IC50 of 5.6 μM for HMG-CoA reductase.
Demonstrates inhibitory activity against cellular steroidogenesis in HepG2 cells with an IC50 of 1.37 μM.
Inhibits cholesterol synthesis from [14C]-Acetate in isolated rat hepatocytes with an IC50 of 0.1 μM.
Aids in lowering cholesterol.
Contributes to the prevention of cardiovascular disease.

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835

Apexbio Technology LLC Molnupiravir(Synonyms: EIDD-2801, MK-4482, Lagevrio, Molnupex, EIDD-1931-isopropyl ester, EIDD-2801 prodrug), 200mg, CAS: 2349386-89-4.

Molnupiravir (CAS 2349386-89-4) is an orally bioavailable nucleoside analog prodrug metabolized intracellularly into an active nucleoside triphosphate derivative Its antiviral effect occurs once incorporated by viral RNA-dependent RNA polymerase into newly synthesized viral RNA inducing an accumulation of mutations that disrupt viral genome fidelity and replication In research applications Molnupiravir is extensively employed for in vitro and in vivo studies investigating antiviral activities replication mechanisms and pharmacological responses especially against RNA viruses such as SARS-CoV-2 influenza virus and other coronaviruses

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836

Ambeed AMBEED

5000848073 2-ETHOXYPYRIDIN-3-AMINE 100MG

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837

Chem-Impex International, Inc. 4-Quinolinecarboxylic acid | MFCD00006782 | 25G

4-Quinolinecarboxylic acid, MFCD00006782, 25G

Pricing & Availability

838

Medchemexpress LLC Pictilisib (dimethanesulfonate) | 957054-33-0 | 99.7% | 705.85 | 200 MG

Pictilisib dimethanesulfonate is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).

Potent inhibitor of PI3Kα/δ with IC50 of 3 nM
Modest selectivity against p110β (11-fold) and p110γ (25-fold)
Reduces tumor cell viability in breast cancer cell lines
Inhibits Akt phosphorylation and downstream targets of Akt signaling
Shows high efficacy of antitumor activity in ZD1839-resistant non-small cell lung cancer (NSCLC) cell lines (A549 and H460)
Highly efficacious in combination with U0126 in inducing cell growth inhibition, G0-G1 arrest, and cell apoptosis
Reduces secreted VEGF after hypoxic/anoxic exposure
Leads to tumor stasis in animal models
Results in tumor regressions during treatment leading to enhanced antitumor responses
Reduces tumor growth and PI3K and HIF-1 pathway activity in tumor-bearing mice

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839

Apexbio Technology LLC AM966 1228690-19-4 200mg

AM966 (CAS 1228690-19-4) is an orally bioavailable small-molecule antagonist that selectively targets Lysophosphatidic acid type 1 receptor (LPA1) AM966 exhibits potent inhibitory activity against LPA1 receptors from humans and mice with IC50 values of approximately 17 nM and 19 nM respectively demonstrating selectivity over other LPA receptor subtypes (LPA2 5) In vitro AM966 blocks LPA-mediated chemotactic responses in IMR-90 human lung fibroblasts A2058 human melanoma cells and CHO cell lines In vivo AM966 effectively attenuates lung fibrosis inflammation and associated weight loss in bleomycin-induced murine pulmonary fibrosis models highlighting its utility in research on fibrotic diseases

Pricing & Availability

840

eMolecules 1408075-13-7 | Cis-3-Fluoro-cyclobutylamine hydrochloride | J & W PharmLab LLC | MFCD23106124 | 125.570 | C4H9ClFN | 96.000 | Cl.N[C@H]1C[C@@H](F)C1 | 100mg | 548147584

Cis-3-Fluoro-cyclobutylamine hydrochloride | J & W PharmLab LLC | 1408075-13-7 | MFCD23106124 | 125.570 | C4H9ClFN | 96.000 | Cl.N[C@H]1C[C@@H](F)C1 | 100mg | 548147584

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Quinolines and derivatives

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Medchemexpress LLC Mebendazole-amine 5mg | 52329-60-9 | 237.26 g/mol | C14H11N3O | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olmutinib | 1353550-13-6 | 99.5% / 99.9% | 486.59 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen Dihydroethidium Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen Dihydroethidium Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Belinostat (PXD101) 414864-00-9 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pravastatin sodium | 81131-70-6 | 99.4% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Molnupiravir(Synonyms: EIDD-2801, MK-4482, Lagevrio, Molnupex, EIDD-1931-isopropyl ester, EIDD-2801 prodrug), 200mg, CAS: 2349386-89-4. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pictilisib (dimethanesulfonate) | 957054-33-0 | 99.7% | 705.85 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC AM966 1228690-19-4 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mebendazole-amine 5mg | 52329-60-9 | 237.26 g/mol | C14H11N3O | 5 MG

Medchemexpress LLC Olmutinib | 1353550-13-6 | 99.5% / 99.9% | 486.59 | 200 MG

AdipoGen Dihydroethidium

AdipoGen Dihydroethidium

Apexbio Technology LLC Belinostat (PXD101) 414864-00-9 200mg

Medchemexpress LLC Pravastatin sodium | 81131-70-6 | 99.4% | 200 MG

Apexbio Technology LLC Molnupiravir(Synonyms: EIDD-2801, MK-4482, Lagevrio, Molnupex, EIDD-1931-isopropyl ester, EIDD-2801 prodrug), 200mg, CAS: 2349386-89-4.

Medchemexpress LLC Pictilisib (dimethanesulfonate) | 957054-33-0 | 99.7% | 705.85 | 200 MG

Apexbio Technology LLC AM966 1228690-19-4 200mg